1-CLAV-457 Dry Syrup MANUFACTURER/ MARKETER C Pharmaceuticals SALT COMPOSITION Amoxycillin (400mg/5ml) + Clavulanic Acid (57mg/5ml) STORAGE Store below 30°C
Your child’s medicine at a glance
1-CLAV-457457 Dry Syrup is an antibiotic medicine that helps treat bacterial infections of the ear, nose, throat, chest, lungs, teeth, skin, and urinary tract. It is capable of killing bacteria that have become resistant to other therapies and thus also helps treat tuberculosis that is resistant to other treatments.
You can give 1-CLAV-457 Dry Syrup to your child with or without food. It is better to give it with food as that helps increase absorption and decrease the risk of stomach upset. The doctor may prescribe giving it two to three times a day. Medicine dose depends on the severity of the infection, its type, and your child’s body weight and age. So, stick to the dose, time, and way prescribed. If your child vomits the medicine within 30 minutes of intake, let the child calm down and repeat the dose. Do not double dose if it's the time for the next dose.
1-CLAV-457 Dry Syrup may cause vomiting, diarrhea, nausea, abdominal pain, and allergy. These side effects should diminish on their own. But, in case they persist or start bothering your child, you must not delay speaking to your child’s doctor.
Share your child’s entire medical history with the doctor, including any previous episode of allergy, heart problem, blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. This information will assist the doctor in making dose alterations and for planning your child’s overall treatment
Uses of 1-CLAV-457 Dry Syrup in children
Also known as TB, Koch's Disease
Description of Bacterial infections
Bacterial infections are caused by bacteria, a kind of microorganisms that are made of only one cell. Bacteria live in all kinds of the environment including extreme hot and cold conditions. Millions of bacteria are present in the environment around us, on our body and inside it. Bacteria are both harmful and useful to us. In fact, only a small number of bacteria are responsible for illnesses. Many are beneficial, such as those involved in immunity, digestion, and production of antibiotics and food products.
Bacteria are important for digestion of food. There are some that fight diseases and those that help make healthful food. Some examples of good bacteria include: 1. Lactobacillus is used in making yogurt and cheese. 2. Escherichia coli are present in intestines and help in digestion of food, and production of vitamin K. 3. Bacteroides thetaiotaomicron and Bacteroides fragilis live in the gut and help in digestion of carbohydrates and sugar transport and utilization
Causes and Risk Factors
Some bacteria cause illness. They invade and quickly multiply in the body to form colonies. When this happens in the respiratory tract, the following diseases may occur: 1. Pharyngitis -- Streptococcus pyogenes 2. Diphtheria -- Corynebacterium diphtheria 3. Pertussis -- Bordetella pertussis 4. Tuberculosis -- Mycobacterium tuberculosis
Bacteria also cause skin infections such as: 1. Leprosy -- Mycobacterium leprae 2. Abscess -- Staphylococcus aureus
Signs and Symptoms
The symptoms of bacterial infection would depend on the condition, the organ affected, and the kind of bacteria causing the infection.
The diagnosis of bacterial infections would depend on the symptomatic history of the patient. The tests that may be done include: 1. Physical examination 2. Blood tests 3. Urine tests 4. Urine culture 5. Gram stain to identify bacteria 6. Toxin assay to look for the toxins made by the bacteria 7. Culture or biopsy of the tissue infected
The treatment will depend on the kind of infection. Antibiotics are usually prescribed to treat bacterial infections. These are medicines that kill the bacteria. They may be given in the oral or injectable form. Some antibiotics that may be prescribed for a bacterial infection may include: 1. Amoxicillin 2. Azithromycin 3. Doxycycline 4. Ofloxacin 5. Tetracycline 6. Gentamycin 7. Metronidazole 8. Clindamycin Supportive therapy may be required for other symptoms, such as fever.
Complications and When Should You See a Doctor
The complications will depend on the kind of bacterial infection. Antibiotics must be taken carefully and for the duration, they are prescribed for. Taking them too frequently, taking them without a prescription or not completing the full course of treatment may lead to a development of antibiotic resistance, where antibiotics fail to kill bacteria. Antibiotic resistance makes treatment of bacterial infections difficult and may prolong the illness and severity.
Fernández-Frackelton M. Bacteria. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA:Elsevier; 2018:chap 121. McAdam AJ, Milner DA, Sharpe AH. Infectious diseases. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 9th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 8.
Benefits of 1-CLAV-457 Dry Syrup for your child
In Treatment of Resistant Tuberculosis (TB)
In multidrug-resistant (MDR) tuberculosis, the causative bacteria produce an enzyme called beta-lactamase. This enzyme breaks down the antibiotics and makes them ineffective. As a result, the bacteria become resistant to the antibiotic being used for treatment. 1-CLAV-457Dry Syrup comprises two active ingredients, amoxycillin and clavulanic acid. While clavulanic acid stops the enzyme from rendering amoxycillin ineffective, amoxycillin works towards killing the tuberculosis-causing bacteria. This makes the combination of amoxycillin and clavulanic acid an effective treatment for resistant tuberculosis.
Side effects of 1-CLAV-457 Dry Syrup in children
1-CLAV-457 Dry Syrup does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Bactoclav
How can I give 1-CLAV-457 Dry Syrup to my child?
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. 1-CLAV-457 Dry Syrup is to be taken with food.
How Bactoclav Oral Suspension works
1-CLAV-457 Dry Syrup is an antibiotic. It has two active agents, amoxycillin and clavulanic acid. Amoxycillin works by preventing the formation of the bacterial protective covering (cell wall) essential for the survival of the bacteria. Whereas, clavulanic acid serves a special purpose of inhibiting an enzyme (beta-lactamase) that is produced by resistant bacteria. This makes the combination of amoxycillin and clavulanic acid an effective line of treatment for many types of infections.
Bactoclav DS 457 Dry Syrup should be used with caution in patients with kidney disease. Dose adjustment of Bactoclav DS 457 Dry Syrup may be needed. Please consult your doctor.
Bactoclav DS 457 Dry Syrup should be used with caution in patients with liver disease. Dose adjustment of Bactoclav DS 457 Dry Syrup may be needed. Please consult your doctor. Consult with your child’s doctor before giving Bactoclav DS 457 Dry Syrup to your child in case of a severe form of liver disease.
What if I forget to give Bactoclav DS 457 Dry Syrup to my child?
You can give the missed dose as soon as you remember unless advised otherwise by the doctor. Skip the missed dose if it is almost time for the next dose. Do not give a double dose to catch up and follow the prescribed dosing schedule.